5fe8

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==Crystal structure of human PCAF bromodomain in complex with compound SL1126 (compound 12)==
==Crystal structure of human PCAF bromodomain in complex with compound SL1126 (compound 12)==
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<StructureSection load='5fe8' size='340' side='right' caption='[[5fe8]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='5fe8' size='340' side='right'caption='[[5fe8]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5fe8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FE8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FE8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5fe8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FE8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FE8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5WT:~{N}-(1,4-DIMETHYL-2-OXIDANYLIDENE-QUINOLIN-7-YL)ETHANAMIDE'>5WT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5WT:~{N}-(1,4-DIMETHYL-2-OXIDANYLIDENE-QUINOLIN-7-YL)ETHANAMIDE'>5WT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KAT2B, PCAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fe8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fe8 OCA], [http://pdbe.org/5fe8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fe8 RCSB], [http://www.ebi.ac.uk/pdbsum/5fe8 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fe8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fe8 OCA], [http://pdbe.org/5fe8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fe8 RCSB], [http://www.ebi.ac.uk/pdbsum/5fe8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fe8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5fe8" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5fe8" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Histone acetyltransferase 3D structures|Histone acetyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Histone acetyltransferase]]
[[Category: Histone acetyltransferase]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Bountra, C]]

Revision as of 07:14, 6 May 2020

Crystal structure of human PCAF bromodomain in complex with compound SL1126 (compound 12)

PDB ID 5fe8

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