4z1q
From Proteopedia
(Difference between revisions)
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==Crystal structure of the first bromodomain of human BRD4 bound to benzotriazolo-diazepine scaffold== | ==Crystal structure of the first bromodomain of human BRD4 bound to benzotriazolo-diazepine scaffold== | ||
- | <StructureSection load='4z1q' size='340' side='right' caption='[[4z1q]], [[Resolution|resolution]] 1.40Å' scene=''> | + | <StructureSection load='4z1q' size='340' side='right'caption='[[4z1q]], [[Resolution|resolution]] 1.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4z1q]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z1Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z1Q FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4z1q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z1Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z1Q FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=558:5-[(4R)-6-(4-CHLOROPHENYL)-1,4-DIMETHYL-5,6-DIHYDRO-4H-[1,2,4]TRIAZOLO[4,3-A][1,5]BENZODIAZEPIN-8-YL]PYRIDIN-2-AMINE'>558</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=558:5-[(4R)-6-(4-CHLOROPHENYL)-1,4-DIMETHYL-5,6-DIHYDRO-4H-[1,2,4]TRIAZOLO[4,3-A][1,5]BENZODIAZEPIN-8-YL]PYRIDIN-2-AMINE'>558</scene></td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z1q OCA], [http://pdbe.org/4z1q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z1q RCSB], [http://www.ebi.ac.uk/pdbsum/4z1q PDBsum]</span></td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z1q OCA], [http://pdbe.org/4z1q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z1q RCSB], [http://www.ebi.ac.uk/pdbsum/4z1q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z1q ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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==See Also== | ==See Also== | ||
- | *[[Bromodomain-containing protein|Bromodomain-containing protein]] | + | *[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Human]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Bellon, S F]] | [[Category: Bellon, S F]] | ||
[[Category: Poy, F]] | [[Category: Poy, F]] |
Revision as of 06:58, 19 June 2019
Crystal structure of the first bromodomain of human BRD4 bound to benzotriazolo-diazepine scaffold
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Categories: Human | Large Structures | Bellon, S F | Poy, F | Setser, J W | Tang, Y | Bromodomain | Transcription