This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4yqn
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds== | ==Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds== | ||
| - | <StructureSection load='4yqn' size='340' side='right' caption='[[4yqn]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='4yqn' size='340' side='right'caption='[[4yqn]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4yqn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YQN FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4yqn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haein Haein]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YQN FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4H3:6-{[(1R,3S,4R)-3-HYDROXY-4-(HYDROXYMETHYL)CYCLOPENTYL]AMINO}PYRIDINE-3-CARBOXAMIDE'>4H3</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4H3:6-{[(1R,3S,4R)-3-HYDROXY-4-(HYDROXYMETHYL)CYCLOPENTYL]AMINO}PYRIDINE-3-CARBOXAMIDE'>4H3</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ypw|4ypw]], [[4ypx|4ypx]], [[4ypz|4ypz]], [[4yq0|4yq0]], [[4yq1|4yq1]], [[4yq2|4yq2]], [[4yq3|4yq3]], [[4yq4|4yq4]], [[4yq5|4yq5]], [[4yq6|4yq6]], [[4yq7|4yq7]], [[4yq8|4yq8]], [[4yq9|4yq9]], [[4yqa|4yqa]], [[4yqb|4yqb]], [[4yqc|4yqc]], [[4yqd|4yqd]], [[4yqg|4yqg]], [[4yqi|4yqi]], [[4yqj|4yqj]], [[4yqk|4yqk]], [[4yql|4yql]], [[4yqo|4yqo]], [[4yqp|4yqp]], [[4yqq|4yqq]], [[4yqr|4yqr]], [[4yqs|4yqs]], [[4yqt|4yqt]], [[4ypy|4ypy]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ypw|4ypw]], [[4ypx|4ypx]], [[4ypz|4ypz]], [[4yq0|4yq0]], [[4yq1|4yq1]], [[4yq2|4yq2]], [[4yq3|4yq3]], [[4yq4|4yq4]], [[4yq5|4yq5]], [[4yq6|4yq6]], [[4yq7|4yq7]], [[4yq8|4yq8]], [[4yq9|4yq9]], [[4yqa|4yqa]], [[4yqb|4yqb]], [[4yqc|4yqc]], [[4yqd|4yqd]], [[4yqg|4yqg]], [[4yqi|4yqi]], [[4yqj|4yqj]], [[4yqk|4yqk]], [[4yql|4yql]], [[4yqo|4yqo]], [[4yqp|4yqp]], [[4yqq|4yqq]], [[4yqr|4yqr]], [[4yqs|4yqs]], [[4yqt|4yqt]], [[4ypy|4ypy]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmD, HI_0202 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=71421 HAEIN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yqn OCA], [http://pdbe.org/4yqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yqn RCSB], [http://www.ebi.ac.uk/pdbsum/4yqn PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yqn OCA], [http://pdbe.org/4yqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yqn RCSB], [http://www.ebi.ac.uk/pdbsum/4yqn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yqn ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN]] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605] | [[http://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN]] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[TRNA methyltransferase|TRNA methyltransferase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Haein]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Bonnette, W G]] | [[Category: Bonnette, W G]] | ||
[[Category: Elkins, P A]] | [[Category: Elkins, P A]] | ||
Revision as of 06:34, 12 June 2019
Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
| |||||||||||
