5ign
From Proteopedia
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==Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe== | ==Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe== | ||
| - | <StructureSection load='5ign' size='340' side='right' caption='[[5ign]], [[Resolution|resolution]] 1.70Å' scene=''> | + | <StructureSection load='5ign' size='340' side='right'caption='[[5ign]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ign]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IGN OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5ign]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IGN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IGN FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6B2:N-[(2R,3S)-2-(4-CHLOROPHENYL)-1-(1,4-DIMETHYL-2-OXO-1,2-DIHYDROQUINOLIN-7-YL)-6-OXOPIPERIDIN-3-YL]-2-METHYLPROPANE-1-SULFONAMIDE'>6B2</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6B2:N-[(2R,3S)-2-(4-CHLOROPHENYL)-1-(1,4-DIMETHYL-2-OXO-1,2-DIHYDROQUINOLIN-7-YL)-6-OXOPIPERIDIN-3-YL]-2-METHYLPROPANE-1-SULFONAMIDE'>6B2</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD9, UNQ3040/PRO9856 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ign FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ign OCA], [http://pdbe.org/5ign PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ign RCSB], [http://www.ebi.ac.uk/pdbsum/5ign PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ign ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN]] May play a role in chromatin remodeling and regulation of transcription. | [[http://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN]] May play a role in chromatin remodeling and regulation of transcription. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
Revision as of 07:18, 3 June 2020
Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe
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Categories: Human | Large Structures | Arrowsmith, C H | Bountra, C | Brennan, P E | Clark, P G.K | Delft, F von | Dixon, D J | Edwards, A M | Fedorov, O | Knapp, S | Krojer, T | Newman, J A | Nunez-Alonso, G | Picaud, S | Structural genomic | Tallant, C | Vieira, L C.C | Chromatin regulator | Lysine-acetylated histone binding | Sgc | Transcription
