This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5hmi
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='5hmi' size='340' side='right' caption='[[5hmi]], [[Resolution|resolution]] 1.74Å' scene=''> | <StructureSection load='5hmi' size='340' side='right' caption='[[5hmi]], [[Resolution|resolution]] 1.74Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5hmi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HMI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HMI FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5hmi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HMI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HMI FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=62T:{4-[2-(2-HYDROXYETHOXY)PHENYL]PIPERAZIN-1-YL}[(2R,3S)-2-PROPYL-1-{[4-(TRIFLUOROMETHYL)PYRIDIN-3-YL]CARBONYL}-3-{[5-(TRIFLUOROMETHYL)THIOPHEN-3-YL]OXY}PIPERIDIN-3-YL]METHANONE'>62T</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=62T:{4-[2-(2-HYDROXYETHOXY)PHENYL]PIPERAZIN-1-YL}[(2R,3S)-2-PROPYL-1-{[4-(TRIFLUOROMETHYL)PYRIDIN-3-YL]CARBONYL}-3-{[5-(TRIFLUOROMETHYL)THIOPHEN-3-YL]OXY}PIPERIDIN-3-YL]METHANONE'>62T</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hmk|5hmk]], [[5hmh|5hmh]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hmk|5hmk]], [[5hmh|5hmh]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hmi OCA], [http://pdbe.org/5hmi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hmi RCSB], [http://www.ebi.ac.uk/pdbsum/5hmi PDBsum]</span></td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hmi OCA], [http://pdbe.org/5hmi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hmi RCSB], [http://www.ebi.ac.uk/pdbsum/5hmi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hmi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
| Line 25: | Line 26: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Scapin, G]] | [[Category: Scapin, G]] | ||
[[Category: E3 ubiquitin-protein ligase]] | [[Category: E3 ubiquitin-protein ligase]] | ||
Revision as of 09:59, 22 November 2017
HDM2 in complex with a 3,3-Disubstituted Piperidine
| |||||||||||
