4zsi
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the effector-binding domain of DasR (DasR-EBD) in complex with glucosamine-6-phosphate== | |
| - | + | <StructureSection load='4zsi' size='340' side='right' caption='[[4zsi]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4zsi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZSI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4R1:BETA-GLUCOSAMINE-6-PHOSPHATE'>4R1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLP:GLUCOSAMINE+6-PHOSPHATE'>GLP</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zsi OCA], [http://pdbe.org/4zsi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zsi RCSB], [http://www.ebi.ac.uk/pdbsum/4zsi PDBsum]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DASR_STRCO DASR_STRCO]] Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N-acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin, as well as several genes involved in development, thereby linking carbon availability to morphogenesis. Binds to the DNA consensus sequence 5'-ACTGGTCTAGACCACT-3'.<ref>PMID:15247334</ref> <ref>PMID:16925557</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Fillenberg, S B]] | ||
| + | [[Category: Koerner, S]] | ||
| + | [[Category: Muller, Y A]] | ||
| + | [[Category: Bacterial transcription regulation]] | ||
| + | [[Category: Effector-binding domain]] | ||
| + | [[Category: Glucosamine-6-phosphate]] | ||
| + | [[Category: Gntr/hutc family]] | ||
| + | [[Category: Master regulator]] | ||
| + | [[Category: N-acetylglucosamine utilization]] | ||
| + | [[Category: Repressor]] | ||
| + | [[Category: Transcription]] | ||
| + | [[Category: Transcription factor]] | ||
Revision as of 15:18, 20 June 2016
Crystal structure of the effector-binding domain of DasR (DasR-EBD) in complex with glucosamine-6-phosphate
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