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5bo3
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)== | |
| - | + | <StructureSection load='5bo3' size='340' side='right' caption='[[5bo3]], [[Resolution|resolution]] 1.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5bo3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BO3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7P2:2-[(2-CARBOXYPHENYL)AMINO]-5-(4-PHOSPHONOBUTOXY)BENZOIC+ACID'>7P2</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qr9|3qr9]], [[4ij1|4ij1]], [[5bo2|5bo2]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo3 OCA], [http://pdbe.org/5bo3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bo3 RCSB], [http://www.ebi.ac.uk/pdbsum/5bo3 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Anthranilate phosphoribosyltransferase]] | ||
| + | [[Category: Baker, E N]] | ||
| + | [[Category: Evans, G L]] | ||
| + | [[Category: Lott, J S]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Lobenzarit-like analogue]] | ||
| + | [[Category: Magnesium binding]] | ||
| + | [[Category: Tbsgc]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 06:05, 2 June 2016
Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
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