This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5cgb
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of FimH in complex with heptyl alpha-D-septanoside== | |
| - | + | <StructureSection load='5cgb' size='340' side='right' caption='[[5cgb]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5cgb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CGB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CGB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=51C:(6R)-1,6-ANHYDRO-2-O-HEPTYL-6-(HYDROXYMETHYL)-D-GALACTITOL'>51C</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cgb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cgb OCA], [http://pdbe.org/5cgb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cgb RCSB], [http://www.ebi.ac.uk/pdbsum/5cgb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cgb ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ernst, B]] | ||
| + | [[Category: Fiege, B]] | ||
| + | [[Category: Jakob, R P]] | ||
| + | [[Category: Maier, T]] | ||
| + | [[Category: Peczuh, M]] | ||
| + | [[Category: Preston, R P]] | ||
| + | [[Category: Rabbani, S]] | ||
| + | [[Category: Sager, C P]] | ||
| + | [[Category: Vannam, R]] | ||
| + | [[Category: Zalewski, A]] | ||
| + | [[Category: Zihlmann, P]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Lectin]] | ||
| + | [[Category: Pilus]] | ||
| + | [[Category: Sugar binding protein]] | ||
| + | [[Category: Type 1 fimbriae]] | ||
| + | [[Category: Urinary tract infection]] | ||
| + | [[Category: Uti]] | ||
Revision as of 15:27, 26 July 2016
Crystal structure of FimH in complex with heptyl alpha-D-septanoside
| |||||||||||
Categories: Ernst, B | Fiege, B | Jakob, R P | Maier, T | Peczuh, M | Preston, R P | Rabbani, S | Sager, C P | Vannam, R | Zalewski, A | Zihlmann, P | Inhibitor | Lectin | Pilus | Sugar binding protein | Type 1 fimbriae | Urinary tract infection | Uti
