5co5
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of Ac-AChBP in complex with conotoxin GIC== | |
- | + | <StructureSection load='5co5' size='340' side='right' caption='[[5co5]], [[Resolution|resolution]] 2.10Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5co5]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CO5 FirstGlance]. <br> | |
- | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5co5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5co5 OCA], [http://pdbe.org/5co5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5co5 RCSB], [http://www.ebi.ac.uk/pdbsum/5co5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5co5 ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/CA1C_CONGE CA1C_CONGE]] Alpha-conotoxins bind to the nicotinic acetylcholine receptors (nAChR) and inhibit them. This toxin reversibly blocks neuronal nAChRs (alpha-3/beta-2 = alpha-6 or -3/beta-2 or -3 > alpha-3/beta-4 = alpha-4/beta-2). | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Lin, B]] | ||
+ | [[Category: Luo, S L]] | ||
+ | [[Category: Wang, X Q]] | ||
+ | [[Category: Xu, M Y]] | ||
+ | [[Category: Achbp]] | ||
+ | [[Category: Gic]] | ||
+ | [[Category: Metal binding protein-toxin complex]] |
Revision as of 15:29, 26 July 2016
Crystal structure of Ac-AChBP in complex with conotoxin GIC
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