5erp
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human Desmocollin-2 ectodomain fragment EC2-5== | |
| - | + | <StructureSection load='5erp' size='340' side='right' caption='[[5erp]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5erp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ERP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ERP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5eqx|5eqx]], [[5erd|5erd]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5erp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5erp OCA], [http://pdbe.org/5erp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5erp RCSB], [http://www.ebi.ac.uk/pdbsum/5erp PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/DSC2_HUMAN DSC2_HUMAN]] Familial isolated arrhythmogenic ventricular dysplasia, right dominant form;Familial isolated arrhythmogenic ventricular dysplasia, biventricular form;Familial isolated arrhythmogenic ventricular dysplasia, left dominant form. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DSC2_HUMAN DSC2_HUMAN]] Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Brasch, J]] | ||
| + | [[Category: Harrison, O J]] | ||
| + | [[Category: Shapiro, L]] | ||
| + | [[Category: Cell adhesion]] | ||
| + | [[Category: Cell surface]] | ||
| + | [[Category: Desmosome]] | ||
| + | [[Category: Extracellular cadherin domain]] | ||
Revision as of 22:24, 20 June 2016
Crystal structure of human Desmocollin-2 ectodomain fragment EC2-5
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