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5ha7
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Human Aldose Reductase in Complex with NADP+ and WY14643 in Space Group P212121== | |
| - | + | <StructureSection load='5ha7' size='340' side='right' caption='[[5ha7]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ha7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HA7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HA7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WY1:2-({4-CHLORO-6-[(2,3-DIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL}SULFANYL)ACETIC+ACID'>WY1</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q65|3q65]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ha7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ha7 OCA], [http://pdbe.org/5ha7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ha7 RCSB], [http://www.ebi.ac.uk/pdbsum/5ha7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ha7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN]] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aldehyde reductase]] | ||
| + | [[Category: Balendiran, G K]] | ||
| + | [[Category: Cascio, D]] | ||
| + | [[Category: Sawaya, M R]] | ||
| + | [[Category: Alpha/beta barrel]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 17:08, 3 October 2016
Human Aldose Reductase in Complex with NADP+ and WY14643 in Space Group P212121
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