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5ieq
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-747 1-(4-chlorophenyl)-1H-imidazole== | |
| - | + | <StructureSection load='5ieq' size='340' side='right' caption='[[5ieq]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ieq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IEQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1CI:1-(4-CHLOROPHENYL)-1H-IMIDAZOLE'>1CI</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iuj|4iuj]], [[5if2|5if2]], [[5if5|5if5]], [[5if7|5if7]], [[5if8|5if8]], [[5ifb|5ifb]], [[5ifc|5ifc]], [[5ifd|5ifd]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ieq OCA], [http://pdbe.org/5ieq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ieq RCSB], [http://www.ebi.ac.uk/pdbsum/5ieq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ieq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PA_I33A0 PA_I33A0]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Flu]] | ||
| + | [[Category: Fragment screening]] | ||
| + | [[Category: Fragments of life]] | ||
| + | [[Category: Niaid]] | ||
| + | [[Category: Ssgcid]] | ||
| + | [[Category: Std nmr]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 01:33, 11 March 2017
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-747 1-(4-chlorophenyl)-1H-imidazole
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