5ifc

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'''Unreleased structure'''
 
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The entry 5ifc is ON HOLD until Paper Publication
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==Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole==
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<StructureSection load='5ifc' size='340' side='right' caption='[[5ifc]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ifc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IFC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IFC FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6AR:1-(4-BROMOPHENYL)-1H-IMIDAZOLE'>6AR</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iuj|4iuj]], [[5iex|5iex]], [[5if2|5if2]], [[5if5|5if5]], [[5if7|5if7]], [[5if8|5if8]], [[5ifb|5ifb]], [[5fic|5fic]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ifc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ifc OCA], [http://pdbe.org/5ifc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ifc RCSB], [http://www.ebi.ac.uk/pdbsum/5ifc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ifc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PA_I33A0 PA_I33A0]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication.
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__TOC__
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</StructureSection>
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[[Category: Structural genomic]]
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[[Category: Flu]]
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[[Category: Fragment screening]]
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[[Category: Niaid]]
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[[Category: Ssgcid]]
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[[Category: Std nmr]]
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[[Category: Viral protein]]

Revision as of 01:34, 11 March 2017

Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole

5ifc, resolution 2.65Å

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