5j5p

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'''Unreleased structure'''
 
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The entry 5j5p is ON HOLD until Paper Publication
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==AMP-PNP-stabilized ATPase domain of topoisomerase IV from Streptococcus pneumoniae, complex type I==
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<StructureSection load='5j5p' size='340' side='right' caption='[[5j5p]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5j5p]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/"diplococcus_pneumoniae"_(klein_1884)_weichselbaum_1886 "diplococcus pneumoniae" (klein 1884) weichselbaum 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J5P FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">parE, SP_0852 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 "Diplococcus pneumoniae" (Klein 1884) Weichselbaum 1886])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j5p OCA], [http://pdbe.org/5j5p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j5p RCSB], [http://www.ebi.ac.uk/pdbsum/5j5p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j5p ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Fisher, L M]]
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[[Category: Laponogov, I]]
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[[Category: Pan, X S]]
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[[Category: Sanderson, M R]]
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[[Category: Skamrova, G]]
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[[Category: Umrekar, T]]
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[[Category: Atpase domain]]
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[[Category: Dna binding]]
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[[Category: Isomerase]]
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[[Category: Isomerase-dna complex]]
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[[Category: Streptococcus pneumoniae]]
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[[Category: T-segment]]
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[[Category: Topoisomerase iv]]

Revision as of 04:37, 16 November 2017

AMP-PNP-stabilized ATPase domain of topoisomerase IV from Streptococcus pneumoniae, complex type I

5j5p, resolution 1.97Å

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