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5jcq

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'''Unreleased structure'''
 
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The entry 5jcq is ON HOLD until Paper Publication
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==Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl alpha-D-mannopyrannoside in spacegroup P21==
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<StructureSection load='5jcq' size='340' side='right' caption='[[5jcq]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5jcq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JCQ FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jcq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jcq OCA], [http://pdbe.org/5jcq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jcq RCSB], [http://www.ebi.ac.uk/pdbsum/5jcq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jcq ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
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__TOC__
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</StructureSection>
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[[Category: Ernst, B]]
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[[Category: Jakob, R P]]
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[[Category: Maier, T]]
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[[Category: Rabbani, S]]
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[[Category: Bladder infection]]
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[[Category: Carbohydrate]]
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[[Category: Fimh]]
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[[Category: Lectin]]
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[[Category: Mannose]]
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[[Category: Sugar binding protein]]
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[[Category: Type 1 pilus]]
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[[Category: Uti]]

Revision as of 12:56, 10 May 2017

Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl alpha-D-mannopyrannoside in spacegroup P21

5jcq, resolution 1.60Å

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