Nucleoplasmin
From Proteopedia
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| + | <StructureSection load='1k5j' size='350' side='right' caption='Nucleoplasmin core pentamer (PDB entry [[1k5j]])' scene=''> | ||
== Function == | == Function == | ||
'''Nucleoplasmin''' (Npl) is a molecular chaperone. Npl functions in the proper assembly of nucleosomes and chromatin structures<ref>PMID:15284896</ref>. | '''Nucleoplasmin''' (Npl) is a molecular chaperone. Npl functions in the proper assembly of nucleosomes and chromatin structures<ref>PMID:15284896</ref>. | ||
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== Relevance == | == Relevance == | ||
Apoptotic chromatin condensation, one of the hallmarks of apoptosis, is regulated by Npl. | Apoptotic chromatin condensation, one of the hallmarks of apoptosis, is regulated by Npl. | ||
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==3D structures of nucleoplasmin== | ==3D structures of nucleoplasmin== | ||
Revision as of 10:18, 27 August 2017
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3D structures of nucleoplasmin
1k5j – XlNpl core – Xenopus laevis
2vtx - XlNpl core (mutant)
3t30 – Npl oligomerisation domain - human
1ee5, 1ejy –XlNpl nuclear localization peptide + karyopherin-a
References
- ↑ Prado A, Ramos I, Frehlick LJ, Muga A, Ausio J. Nucleoplasmin: a nuclear chaperone. Biochem Cell Biol. 2004 Aug;82(4):437-45. PMID:15284896 doi:http://dx.doi.org/10.1139/o04-042
