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NAD kinase

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<StructureSection load='1z0u' size='450' side='right' caption='NAD kinase complex with NADP and sulfate (PDB code [[1z0u]]' scene=''>
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<StructureSection load='1z0u' size='450' side='right' caption='NAD kinase complex with NADP and sulfate (PDB code [[1z0u]])' scene='71/715900/Cv/1'>
== Function ==
== Function ==
'''NAD kinase''' (NADK) catalyzes the conversion of ATP and [[NAD]] to ADP and NADP. NADP is critical for metabolism, calcium signaling and anti-inflammatory processes. NADK is regulated by calmodulin-dependent mechanism<ref>PMID:23212377</ref>. See [[NAD]] and [[NAD(P)H]].
'''NAD kinase''' (NADK) catalyzes the conversion of ATP and [[NAD]] to ADP and NADP. NADP is critical for metabolism, calcium signaling and anti-inflammatory processes. NADK is regulated by calmodulin-dependent mechanism<ref>PMID:23212377</ref>. See [[NAD]] and [[NAD(P)H]].

Revision as of 06:59, 30 May 2016

NAD kinase complex with NADP and sulfate (PDB code 1z0u)

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3D structures of NAD kinase

Updated on 30-May-2016

References

  1. Ohashi K, Kawai S, Murata K. Identification and characterization of a human mitochondrial NAD kinase. Nat Commun. 2012;3:1248. doi: 10.1038/ncomms2262. PMID:23212377 doi:http://dx.doi.org/10.1038/ncomms2262
  2. Liu J, Lou Y, Yokota H, Adams PD, Kim R, Kim SH. Crystal structures of an NAD kinase from Archaeoglobus fulgidus in complex with ATP, NAD, or NADP. J Mol Biol. 2005 Nov 25;354(2):289-303. Epub 2005 Sep 30. PMID:16242716 doi:10.1016/j.jmb.2005.09.026

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