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Neprilysin

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== Structural highlights ==
== Structural highlights ==
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A tetrahedrally coordinated Zn atom interacts with the NEP inhibitor and is involved in the catalysis<ref>PMID: 10669592</ref>.
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A <scene name='51/516479/Cv/2'>tetrahedrally coordinated Zn atom interacts with the NEP inhibitor</scene> and is involved in the catalysis<ref>PMID: 10669592</ref>. <scene name='51/516479/Cv/5'>Active site</scene>. Water molecules shown as red spheres.
==3D structures of neprilysin==
==3D structures of neprilysin==

Revision as of 07:29, 1 June 2016

Structure of glycosylated human neprilysin extracellular domain complex with phosphoramidon and Zn+2 ion (grey) (PDB entry 1dmt)

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Michal Harel, Alexander Berchansky, Brenton Horne

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