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5jjs
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Dengue 3 NS5 protein with compound 27== | |
| - | + | <StructureSection load='5jjs' size='340' side='right' caption='[[5jjs]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5jjs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JJS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JJS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6L2:5-[5-(3-HYDROXYPROP-1-YN-1-YL)THIOPHEN-2-YL]-2,4-DIMETHOXY-N-{[(1R,3R)-3-METHOXYCYCLOHEXYL]SULFONYL}BENZAMIDE'>6L2</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jjr|5jjr]]</td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jjs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jjs OCA], [http://pdbe.org/5jjs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jjs RCSB], [http://www.ebi.ac.uk/pdbsum/5jjs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jjs ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q6DLV0_9FLAV Q6DLV0_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Lescar, J]] | [[Category: Lescar, J]] | ||
| + | [[Category: Sahili, A El]] | ||
| + | [[Category: Dengue]] | ||
| + | [[Category: Rdrp]] | ||
| + | [[Category: Transferase-inhibitor complex]] | ||
Revision as of 18:02, 13 July 2016
Dengue 3 NS5 protein with compound 27
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