5l3q
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the GTPase heterodimer of human SRP54 and SRalpha== | |
| - | + | <StructureSection load='5l3q' size='340' side='right' caption='[[5l3q]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5l3q]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L3Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L3Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l3q OCA], [http://pdbe.org/5l3q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l3q RCSB], [http://www.ebi.ac.uk/pdbsum/5l3q PDBsum]</span></td></tr> |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SRP54_HUMAN SRP54_HUMAN]] Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). [[http://www.uniprot.org/uniprot/SRPRA_HUMAN SRPRA_HUMAN]] Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Segnitz, B]] | [[Category: Segnitz, B]] | ||
[[Category: Sinning, I]] | [[Category: Sinning, I]] | ||
| + | [[Category: Wild, K]] | ||
| + | [[Category: Co-translational protein targeting]] | ||
| + | [[Category: Gtpase]] | ||
| + | [[Category: Protein transport]] | ||
| + | [[Category: Signal recognition particle]] | ||
Revision as of 15:29, 20 June 2016
Structure of the GTPase heterodimer of human SRP54 and SRalpha
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