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Forkhead box protein
From Proteopedia
(Difference between revisions)
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| - | <StructureSection load='3co6' size='350' side='right' scene='' caption='Human FoxO1 DNA-binding domain complex with DNA, Ca+2 and chloride ions, [[3co6]]'> | + | <StructureSection load='3co6' size='350' side='right' scene='47/479231/Cv/1' caption='Human FoxO1 DNA-binding domain complex with DNA, Ca+2 and chloride ions, [[3co6]]'> |
== Function == | == Function == | ||
| Line 19: | Line 19: | ||
FOX contain a DNA-binding motif (DBD) of 80-100 amino acids having a winged-helix shape. | FOX contain a DNA-binding motif (DBD) of 80-100 amino acids having a winged-helix shape. | ||
| + | *<scene name='47/479231/Cv/2'>Human FoxO1 DNA-binding domain with DNA, Ca+2 and Cl- ions</scene>. | ||
| + | *<scene name='47/479231/Cv/3'>Ca coordination site</scene>. | ||
| + | *<scene name='47/479231/Cv/4'>Cl coordination site</scene>. Water molecules shown as red spheres. | ||
</StructureSection> | </StructureSection> | ||
==3D structures of FOX== | ==3D structures of FOX== | ||
Revision as of 12:14, 6 June 2016
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3D structures of FOX
Updated on 06-June-2016
References
- ↑ Tuteja G, Kaestner KH. SnapShot: forkhead transcription factors I. Cell. 2007 Sep 21;130(6):1160. PMID:17889656 doi:http://dx.doi.org/10.1016/j.cell.2007.09.005
- ↑ Zhu H. Forkhead box transcription factors in embryonic heart development and congenital heart disease. Life Sci. 2016 Jan 1;144:194-201. doi: 10.1016/j.lfs.2015.12.001. Epub 2015 Dec, 2. PMID:26656470 doi:http://dx.doi.org/10.1016/j.lfs.2015.12.001
