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PDZ and LIM domain protein

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<StructureSection load='2pa1' size='350' side='right' caption='Structure of PDZ and LIM domain protein 2 PDZ domain with C-terminal of β-tropomyosin and Cl- ions (PDB entry [[2pa1]])' scene=''>
<StructureSection load='2pa1' size='350' side='right' caption='Structure of PDZ and LIM domain protein 2 PDZ domain with C-terminal of β-tropomyosin and Cl- ions (PDB entry [[2pa1]])' scene=''>
== Function ==
== Function ==
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'''PDZ and LIM domain proteins''' (PDLIM) contain PDZ and LIM domains. PDLIM binds α-actinin via its PDZ domain and other proteins via its LIM domain. PDLIM is implicated in cardiac and skeletal muscle structure.<br /> For details on PDLIM1 see [[Group:MUZIC:ALP]].<br />For details on PDLIM see [[Group:MUZIC:ZASP]] and [[Group:MUZIC:Enigma Family]].
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'''PDZ and LIM domain proteins''' (PDLIM) contain PDZ and LIM domains. PDLIM binds α-actinin via its PDZ domain and other proteins via its LIM domain. PDLIM is implicated in cardiac and skeletal muscle structure<ref>PMID:17767364</ref>.<br /> For details on PDLIM1 see [[Group:MUZIC:ALP]].<br />For details on PDLIM see [[Group:MUZIC:ZASP]] and [[Group:MUZIC:Enigma Family]].
*'''PDLIM1''' promotes cell attachment at the cytoskeleton.<br />
*'''PDLIM1''' promotes cell attachment at the cytoskeleton.<br />
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**[[1rgw]] – hPDLIM PDZ domain - NMR<br />
**[[1rgw]] – hPDLIM PDZ domain - NMR<br />
}}
}}
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:22, 15 June 2016

Structure of PDZ and LIM domain protein 2 PDZ domain with C-terminal of β-tropomyosin and Cl- ions (PDB entry 2pa1)

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3D structures of PDZ and LIM domain protein

Updated on 15-June-2016

References

  1. ↑ te Velthuis AJ, Bagowski CP. PDZ and LIM domain-encoding genes: molecular interactions and their role in development. ScientificWorldJournal. 2007 Sep 1;7:1470-92. PMID:17767364 doi:10.1100/tsw.2007.232

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Michal Harel, Alexander Berchansky

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