5ce1
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Serine protease Hepsin in complex with Inhibitor== | |
| - | + | <StructureSection load='5ce1' size='340' side='right' caption='[[5ce1]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ce1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CE1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CE1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=50K:2-[6-(1-HYDROXYCYCLOHEXYL)PYRIDIN-2-YL]-1H-INDOLE-5-CARBOXIMIDAMIDE'>50K</scene></td></tr> | |
| - | [[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hepsin Hepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.106 3.4.21.106] </span></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ce1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ce1 OCA], [http://pdbe.org/5ce1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ce1 RCSB], [http://www.ebi.ac.uk/pdbsum/5ce1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ce1 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HEPS_HUMAN HEPS_HUMAN]] Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL.<ref>PMID:21875933</ref> <ref>PMID:15839837</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Hepsin]] | ||
[[Category: Anirudha, L]] | [[Category: Anirudha, L]] | ||
| + | [[Category: Anita, R C]] | ||
| + | [[Category: Rao, K N]] | ||
[[Category: Sangeetha, R]] | [[Category: Sangeetha, R]] | ||
| - | [[Category: | + | [[Category: Subramnay, H]] |
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Prostate cancer]] | ||
| + | [[Category: Serine protease]] | ||
Revision as of 17:57, 13 July 2016
Crystal Structure of Serine protease Hepsin in complex with Inhibitor
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