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5d0b

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'''Unreleased structure'''
 
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The entry 5d0b is ON HOLD until Oct 03 2017
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==Crystal structure of epoxyqueuosine reductase with a tRNA-TYR epoxyqueuosine-modified tRNA stem loop==
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<StructureSection load='5d0b' size='340' side='right' caption='[[5d0b]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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Authors: Dowling, D.P., Miles, Z.D., Kohrer, C., Bandarian, V., Drennan, C.L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5d0b]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D0B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D0B FirstGlance]. <br>
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Description: Crystal structure of epoxyqueuosine reductase with a tRNA-TYR epoxyqueuosine-modified tRNA stem loop
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=56B:2-AMINO-5-({[(1S,4S,5R)-4,5-DIHYDROXYCYCLOPENT-2-EN-1-YL]AMINO}METHYL)-7-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE'>56B</scene></td></tr>
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[[Category: Drennan, C.L]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5d08|5d08]], [[5d0a|5d0a]]</td></tr>
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[[Category: Miles, Z.D]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Epoxyqueuosine_reductase Epoxyqueuosine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.99.6 1.17.99.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d0b OCA], [http://pdbe.org/5d0b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d0b RCSB], [http://www.ebi.ac.uk/pdbsum/5d0b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d0b ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/QUEG_BACSU QUEG_BACSU]] Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).[HAMAP-Rule:MF_00916]<ref>PMID:21502530</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Epoxyqueuosine reductase]]
[[Category: Bandarian, V]]
[[Category: Bandarian, V]]
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[[Category: Dowling, D P]]
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[[Category: Drennan, C L]]
[[Category: Kohrer, C]]
[[Category: Kohrer, C]]
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[[Category: Dowling, D.P]]
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[[Category: Miles, Z D]]
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[[Category: B12]]
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[[Category: Heat-domain]]
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[[Category: Oxidoreductase-rna complex]]
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[[Category: Queuosine]]
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[[Category: Trna modification]]

Revision as of 17:02, 3 October 2016

Crystal structure of epoxyqueuosine reductase with a tRNA-TYR epoxyqueuosine-modified tRNA stem loop

5d0b, resolution 2.65Å

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