5hde
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of PTPN12 Catalytic Domain== | |
| - | + | <StructureSection load='5hde' size='340' side='right' caption='[[5hde]], [[Resolution|resolution]] 1.62Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5hde]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HDE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSP:S-PHOSPHOCYSTEINE'>CSP</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hde OCA], [http://pdbe.org/5hde PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hde RCSB], [http://www.ebi.ac.uk/pdbsum/5hde PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hde ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PTN12_HUMAN PTN12_HUMAN]] Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.<ref>PMID:17329398</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Protein-tyrosine-phosphatase]] | ||
| + | [[Category: Dong, H]] | ||
[[Category: Li, S]] | [[Category: Li, S]] | ||
| - | [[Category: Dong, H]] | ||
[[Category: Shi, J]] | [[Category: Shi, J]] | ||
| + | [[Category: Dephosphorylation]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Protein tyrosine phosphatase]] | ||
| + | [[Category: Ptp]] | ||
| + | [[Category: Ptpn12]] | ||
Revision as of 00:40, 19 January 2017
Crystal Structure of PTPN12 Catalytic Domain
| |||||||||||
