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5iuj
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the DesK-DesR complex in the phosphotransfer state with low Mg2+ (20 mM)== | |
| - | + | <StructureSection load='5iuj' size='340' side='right' caption='[[5iuj]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5iuj]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IUJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iuk|5iuk]], [[5iul|5iul]], [[5ium|5ium]], [[5iun|5iun]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuj OCA], [http://pdbe.org/5iuj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iuj RCSB], [http://www.ebi.ac.uk/pdbsum/5iuj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iuj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DESK_BACSU DESK_BACSU]] Member of the two-component regulatory system DesR/DesK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation.<ref>PMID:11285232</ref> <ref>PMID:11717295</ref> <ref>PMID:12207704</ref> <ref>PMID:14734164</ref> <ref>PMID:15090506</ref> [[http://www.uniprot.org/uniprot/DESR_BACSU DESR_BACSU]] Member of the two-component regulatory system DesR/DesK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase.<ref>PMID:11285232</ref> <ref>PMID:11717295</ref> <ref>PMID:12207704</ref> <ref>PMID:14734164</ref> <ref>PMID:15090506</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Histidine kinase]] | ||
| + | [[Category: Buschiazzo, A]] | ||
| + | [[Category: Imelio, J A]] | ||
[[Category: Larrieux, N]] | [[Category: Larrieux, N]] | ||
| - | [[Category: Imelio, J.A]] | ||
| - | [[Category: Buschiazzo, A]] | ||
[[Category: Trajtenberg, F]] | [[Category: Trajtenberg, F]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Phosphotransfer]] | ||
| + | [[Category: Phosphotransfer complex]] | ||
| + | [[Category: Response regulator]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Two-component regulatory system]] | ||
Revision as of 21:40, 22 December 2016
Crystal structure of the DesK-DesR complex in the phosphotransfer state with low Mg2+ (20 mM)
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