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5jzq
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals massive presence of multiple conformations== | |
| + | <StructureSection load='5jzq' size='340' side='right' caption='[[5jzq]], [[Resolution|resolution]] 0.78Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5jzq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JZQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JZQ FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vtu|1vtu]], [[3p4j|3p4j]], [[1ick|1ick]], [[4hif|4hif]], [[4hig|4hig]], [[4r15|4r15]], [[5ebi|5ebi]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jzq OCA], [http://pdbe.org/5jzq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jzq RCSB], [http://www.ebi.ac.uk/pdbsum/5jzq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jzq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of a Z-DNA hexamer duplex d(CGCGCG)(2) determined at ultra high resolution of 0.55 A and refined without restraints, displays a high degree of regularity and rigidity in its stereochemistry, in contrast to the more flexible B-DNA duplexes. The estimations of standard uncertainties of all individually refined parameters, obtained by full-matrix least-squares optimization, are comparable with values that are typical for small-molecule crystallography. The Z-DNA model generated with ultra high-resolution diffraction data can be used to revise the stereochemical restraints applied in lower resolution refinements. Detailed comparisons of the stereochemical library values with the present accurate Z-DNA parameters, shows in general a good agreement, but also reveals significant discrepancies in the description of guanine-sugar valence angles and in the geometry of the phosphate groups. | ||
| - | + | High regularity of Z-DNA revealed by ultra high-resolution crystal structure at 0.55 A.,Brzezinski K, Brzuszkiewicz A, Dauter M, Kubicki M, Jaskolski M, Dauter Z Nucleic Acids Res. 2011 Aug 1;39(14):6238-48. Epub 2011 Apr 1. PMID:21459852<ref>PMID:21459852</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 5jzq" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Drozdzal, P]] | ||
| + | [[Category: Gilski, M]] | ||
| + | [[Category: Jaskolski, M]] | ||
| + | [[Category: Ab initio method]] | ||
| + | [[Category: Centrosymmetric space group]] | ||
| + | [[Category: Disorder]] | ||
| + | [[Category: Dna]] | ||
| + | [[Category: Dna enantiomer]] | ||
| + | [[Category: Dual-space method]] | ||
| + | [[Category: L-ribose nucleic acid]] | ||
| + | [[Category: Macromolecular phase problem]] | ||
| + | [[Category: Racemate]] | ||
| + | [[Category: Self-complementary duplex]] | ||
| + | [[Category: Z-dna duplex]] | ||
Revision as of 19:51, 9 December 2016
Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals massive presence of multiple conformations
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