This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5l5m
From Proteopedia
(Difference between revisions)
m (Protected "5l5m" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Plexin A4 full extracellular region, domains 1 to 7 modeled, data to 8 angstrom, spacegroup P4(3)2(1)2== | |
| - | + | <StructureSection load='5l5m' size='340' side='right' caption='[[5l5m]], [[Resolution|resolution]] 8.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5l5m]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L5M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L5M FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l5m OCA], [http://pdbe.org/5l5m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l5m RCSB], [http://www.ebi.ac.uk/pdbsum/5l5m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l5m ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PLXA4_MOUSE PLXA4_MOUSE]] Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.<ref>PMID:12591607</ref> <ref>PMID:18262512</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Coles, C H]] | ||
| + | [[Category: Gilbert, R J.C]] | ||
| + | [[Category: Janssen, B J.C]] | ||
| + | [[Category: Jones, E Y]] | ||
| + | [[Category: Kaufmann, R]] | ||
| + | [[Category: Kong, Y]] | ||
| + | [[Category: Malinauskas, T]] | ||
| + | [[Category: Ni, T]] | ||
| + | [[Category: Padilla-Parra, S]] | ||
| + | [[Category: Pasterkamp, R J]] | ||
| + | [[Category: Vangoor, V R]] | ||
| + | [[Category: Axon guidance]] | ||
| + | [[Category: Receptor]] | ||
| + | [[Category: Signaling]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 18:05, 13 July 2016
Plexin A4 full extracellular region, domains 1 to 7 modeled, data to 8 angstrom, spacegroup P4(3)2(1)2
| |||||||||||
