1jgs

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[[Image:1jgs.jpg|left|200px]]
[[Image:1jgs.jpg|left|200px]]
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{{Structure
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|PDB= 1jgs |SIZE=350|CAPTION= <scene name='initialview01'>1jgs</scene>, resolution 2.3&Aring;
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The line below this paragraph, containing "STRUCTURE_1jgs", creates the "Structure Box" on the page.
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{{STRUCTURE_1jgs| PDB=1jgs | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [http://www.ebi.ac.uk/pdbsum/1jgs PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB]</span>
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'''Multiple Antibiotic Resistance Repressor, MarR'''
'''Multiple Antibiotic Resistance Repressor, MarR'''
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[[Category: Mealy, T R.]]
[[Category: Mealy, T R.]]
[[Category: Seaton, B A.]]
[[Category: Seaton, B A.]]
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[[Category: antibiotic resistance]]
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[[Category: Antibiotic resistance]]
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[[Category: dna-binding]]
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[[Category: Dna-binding]]
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[[Category: repressor]]
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[[Category: Repressor]]
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[[Category: transcription regulation]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:12:19 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:33:25 2008''
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Revision as of 18:12, 2 May 2008

Template:STRUCTURE 1jgs

Multiple Antibiotic Resistance Repressor, MarR


Overview

MarR is a regulator of multiple antibiotic resistance in Escherichia coli. It is the prototypical member of the MarR family of regulatory proteins found in bacteria and archaea that play important roles in the development of antibiotic resistance, a global health problem. Here we describe the crystal structure of the MarR protein, determined at a resolution of 2.3 A. This is the first reported crystal structure of a member of this newly-described protein family. The structure shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.

About this Structure

1JGS is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution., Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF, Nat Struct Biol. 2001 Aug;8(8):710-4. PMID:11473263 Page seeded by OCA on Fri May 2 21:12:19 2008

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