1jh3

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[[Image:1jh3.gif|left|200px]]
[[Image:1jh3.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1jh3 |SIZE=350|CAPTION= <scene name='initialview01'>1jh3</scene>
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The line below this paragraph, containing "STRUCTURE_1jh3", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND=
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= tyrS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 Geobacillus stearothermophilus])
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|DOMAIN=
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{{STRUCTURE_1jh3| PDB=1jh3 | SCENE= }}
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|RELATEDENTRY=[[2ts1|2TS1]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jh3 OCA], [http://www.ebi.ac.uk/pdbsum/1jh3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1jh3 RCSB]</span>
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'''Solution structure of tyrosyl-tRNA synthetase C-terminal domain.'''
'''Solution structure of tyrosyl-tRNA synthetase C-terminal domain.'''
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[[Category: Pintar, A.]]
[[Category: Pintar, A.]]
[[Category: Prochnicka-Chalufour, A.]]
[[Category: Prochnicka-Chalufour, A.]]
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[[Category: aminoacyl-trna synthetase]]
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[[Category: Aminoacyl-trna synthetase]]
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[[Category: anticodon-arm binding domain]]
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[[Category: Anticodon-arm binding domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:12:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:33:33 2008''
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Revision as of 18:12, 2 May 2008

Image:1jh3.gif

Template:STRUCTURE 1jh3

Solution structure of tyrosyl-tRNA synthetase C-terminal domain.


Overview

The structure of a recombinant protein, TyrRS(delta4), corresponding to the anticodon arm binding domain of Bacillus stearothermophilus tyrosyl-tRNA synthetase, has been solved, and its dynamics have been studied by nuclear magnetic resonance (NMR). It is the first structure described for such a domain of a tyrosyl-tRNA synthetase. It consists of a five-stranded beta sheet, packed against two alpha helices on one side and one alpha helix on the other side. A large part of the domain is structurally similar to other functionally unrelated RNA binding proteins. The basic residues known to be essential for tRNA binding and charging are exposed to the solvent on the same face of the molecule. The structure of TyrRS(delta4), together with previous mutagenesis data, allows one to delineate the region of interaction with tRNATyr.

About this Structure

1JH3 is a Single protein structure of sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

Structure and dynamics of the anticodon arm binding domain of Bacillus stearothermophilus Tyrosyl-tRNA synthetase., Guijarro JI, Pintar A, Prochnicka-Chalufour A, Guez V, Gilquin B, Bedouelle H, Delepierre M, Structure. 2002 Mar;10(3):311-7. PMID:12005430 Page seeded by OCA on Fri May 2 21:12:47 2008

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