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Phosphotransferase

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* '''Aminoglycoside PT''' (AGPT) inactivate aminoglycoside antibiotics by phosphorylation.<br />
* '''Aminoglycoside PT''' (AGPT) inactivate aminoglycoside antibiotics by phosphorylation.<br />
* '''Phosphoenolpyruvate-protein PT''' (PEP) catalyzes the phosphorylation of protein histidine residues.<br />
* '''Phosphoenolpyruvate-protein PT''' (PEP) catalyzes the phosphorylation of protein histidine residues.<br />
-
* '''Sporulation initiation PT''' (Spo) are elements in the phosphorelay system which regulates the initiation of sporulation.<br />
+
* '''Sporulation initiation PT''' (Spo0B, Spo0F) are elements in the phosphorelay system which regulates the initiation of sporulation.<br />
See: <br />
See: <br />
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**[[1c02]] - PT - yeast<br />
**[[1c02]] - PT - yeast<br />
**[[3n9x]] – PT – ''Plasmodium berghei''<br />
**[[3n9x]] – PT – ''Plasmodium berghei''<br />
-
**[[1fyn]] – PT SH3 domain + polyproline peptide - human<br />
+
**[[1fyn]] – PT fyn SH3 domain + polyproline peptide - human<br />
*'''Aminoglycoside phosphotransferase'''
*'''Aminoglycoside phosphotransferase'''
Line 105: Line 105:
**[[4jbw]] – EcPEP glucose-specific IIA + Malf + Malg + Malk<br />
**[[4jbw]] – EcPEP glucose-specific IIA + Malf + Malg + Malk<br />
-
*'''Sporulation initiation phospotransferase'''
+
*'''Sporulation initiation phosphotransferase'''
-
**[[1f51]], [[1pey]], [[2ftk]] – BsPT sporulation initiation<br />
+
**[[1f51]] – BsSpo0B + Spo0F<br />
-
**[[1pux]] - BsPT sporulation initiation – NMR<br />
+
**[[2ftk]] – BsSpo0B + Spo0F (mutant)<br />
-
**[[2jvi]], [[2jvj]], [[2jvk]] - BsPT sporulation initiation (mutant) – NMR<br />
+
**[[1pey]], [[1nat]] – BsPT Spo0F<br />
-
**[[3q15]] - BsPT sporulation initiation + response regulator aspartate phosphatase<br />
+
**[[1srr]] - BsPT Spo0F (mutant) <br />
 +
**[[1pux]], [[1fsp]], [[2fsp]] - BsPT Spo0F – NMR<br />
 +
**[[2jvi]], [[2jvj]], [[2jvk]] - BsPT Spo0F (mutant) – NMR<br />
 +
**[[3q15]] - BsPT spo0F + response regulator aspartate phosphatase<br />
}}
}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Revision as of 08:53, 3 July 2016

Template:STRUCTURE 3q2m

Phosphotransferase (PT) are enzymes which catalyze phosphorylation reactions. The acceptor group can be alcohol, carboxy, nitrogenous, phosphate or a pair ofd groups.

  • Aminoglycoside PT (AGPT) inactivate aminoglycoside antibiotics by phosphorylation.
  • Phosphoenolpyruvate-protein PT (PEP) catalyzes the phosphorylation of protein histidine residues.
  • Sporulation initiation PT (Spo0B, Spo0F) are elements in the phosphorelay system which regulates the initiation of sporulation.

See:

3D structures of phosphotransferase

Updated on 03-July-2016

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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