Plasminogen activator inhibitor
From Proteopedia
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'''Plasminogen activator inhibitor''' (PAI) is a serine protease inhibitor.<br /> | '''Plasminogen activator inhibitor''' (PAI) is a serine protease inhibitor.<br /> | ||
* '''PAI-1''' inhibits tissue plasminogen activator and urokinase<ref>PMID:15634264</ref>.<br /> | * '''PAI-1''' inhibits tissue plasminogen activator and urokinase<ref>PMID:15634264</ref>.<br /> | ||
| - | * '''PAI-2''' is secreted by the placenta and is present during pregnancy.<br /> | + | * '''PAI-2''' is secreted by the placenta and is present during pregnancy<ref>PMID:18690354</ref>.<br /> |
| - | * '''PAI-3''' inhibits enzymes in blood coagulation. | + | * '''PAI-3''' inhibits enzymes in blood coagulation<ref>PMID:12139754</ref>. |
== 3D Structures of plasminogen activator inhibitor == | == 3D Structures of plasminogen activator inhibitor == | ||
Revision as of 06:57, 5 July 2016
Plasminogen activator inhibitor (PAI) is a serine protease inhibitor.
- PAI-1 inhibits tissue plasminogen activator and urokinase[1].
- PAI-2 is secreted by the placenta and is present during pregnancy[2].
- PAI-3 inhibits enzymes in blood coagulation[3].
3D Structures of plasminogen activator inhibitor
Updated on 05-July-2016
References
- ↑ Lijnen HR. Pleiotropic functions of plasminogen activator inhibitor-1. J Thromb Haemost. 2005 Jan;3(1):35-45. PMID:15634264 doi:http://dx.doi.org/10.1111/j.1538-7836.2004.00827.x
- ↑ Lobov S, Croucher DR, Saunders DN, Ranson M. Plasminogen activator inhibitor type 2 inhibits cell surface associated tissue plasminogen activator in vitro: potential receptor interactions. Thromb Haemost. 2008 Aug;100(2):319-29. PMID:18690354
- ↑ Meijers JC, Marquart JA, Bertina RM, Bouma BN, Rosendaal FR. Protein C inhibitor (plasminogen activator inhibitor-3) and the risk of venous thrombosis. Br J Haematol. 2002 Aug;118(2):604-9. PMID:12139754
