1jkw
From Proteopedia
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[[Image:1jkw.gif|left|200px]] | [[Image:1jkw.gif|left|200px]] | ||
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'''STRUCTURE OF CYCLIN MCS2''' | '''STRUCTURE OF CYCLIN MCS2''' | ||
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[[Category: Poterszman, A.]] | [[Category: Poterszman, A.]] | ||
[[Category: Thierry, J C.]] | [[Category: Thierry, J C.]] | ||
- | [[Category: | + | [[Category: Cell cycle]] |
- | [[Category: | + | [[Category: Cell division]] |
- | [[Category: | + | [[Category: Cyclin]] |
- | [[Category: | + | [[Category: Nuclear protein]] |
- | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:20:46 2008'' | |
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + |
Revision as of 18:20, 2 May 2008
STRUCTURE OF CYCLIN MCS2
Overview
The crystal structure of human cyclin H has been solved at 2.6 A resolution by the MIR method and refined to an R-factor of 23.1%. The core of the molecule consists of two helical repeats adopting the canonical cyclin fold already observed in the structures of cyclin A [Brown et al. (1995) Structure 3, 1235-1247; Jeffrey et al. (1995) Nature 376, 313-320; Russo et al. (1996) Nature 382, 325-331] and TFIIB [Nikoilov et al. (1995) Nature 377, 119-128]. The N-terminal and C-terminal residues form a new domain built on two long helices interacting essentially with the first repeat of the molecule.
About this Structure
1JKW is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
The crystal structure of human cyclin H., Andersen G, Poterszman A, Egly JM, Moras D, Thierry JC, FEBS Lett. 1996 Nov 11;397(1):65-9. PMID:8941715 Page seeded by OCA on Fri May 2 21:20:46 2008