5d1q
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==IsdB NEAT2 bound by clone D2-06== | |
| - | + | <StructureSection load='5d1q' size='340' side='right' caption='[[5d1q]], [[Resolution|resolution]] 3.22Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5d1q]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D1Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D1Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5d1z|5d1z]], [[5d1x|5d1x]]</td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d1q OCA], [http://pdbe.org/5d1q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d1q RCSB], [http://www.ebi.ac.uk/pdbsum/5d1q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d1q ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ISDB_STAAB ISDB_STAAB]] Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Deng, X]] | [[Category: Deng, X]] | ||
| + | [[Category: Germline encoded]] | ||
| + | [[Category: Igvh1-69]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: Isdb neat2]] | ||
Revision as of 16:21, 10 August 2016
IsdB NEAT2 bound by clone D2-06
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