5d1z
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==IsdB NEAT1 bound by clone D4-10== | |
- | + | <StructureSection load='5d1z' size='340' side='right' caption='[[5d1z]], [[Resolution|resolution]] 3.17Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5d1z]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D1Z FirstGlance]. <br> | |
- | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5d1x|5d1x]], [[5diq|5diq]]</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d1z OCA], [http://pdbe.org/5d1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d1z RCSB], [http://www.ebi.ac.uk/pdbsum/5d1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d1z ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/ISDB_STAAS ISDB_STAAS]] Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity). | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Deng, X]] | ||
+ | [[Category: Germline encoded]] | ||
+ | [[Category: Immune system]] | ||
+ | [[Category: Isdb]] | ||
+ | [[Category: Neat1]] |
Revision as of 15:27, 14 September 2016
IsdB NEAT1 bound by clone D4-10
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Categories: Deng, X | Germline encoded | Immune system | Isdb | Neat1