This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5cf2
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal Structure of the I80Y/L114V/I116V mutant of LEH== | ==Crystal Structure of the I80Y/L114V/I116V mutant of LEH== | ||
| - | <StructureSection load='5cf2' size='340' side='right' caption='[[5cf2]], [[Resolution|resolution]] 3.00Å' scene=''> | + | <StructureSection load='5cf2' size='340' side='right'caption='[[5cf2]], [[Resolution|resolution]] 3.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5cf2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CF2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CF2 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5cf2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CF2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CF2 FirstGlance]. <br> |
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cf1|5cf1]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cf1|5cf1]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">limA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 "Mycobacterium erythropolis" Gray and Thornton 1928])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Limonene-1,2-epoxide_hydrolase Limonene-1,2-epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.8 3.3.2.8] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Limonene-1,2-epoxide_hydrolase Limonene-1,2-epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.8 3.3.2.8] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cf2 OCA], [http://pdbe.org/5cf2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cf2 RCSB], [http://www.ebi.ac.uk/pdbsum/5cf2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cf2 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cf2 OCA], [http://pdbe.org/5cf2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cf2 RCSB], [http://www.ebi.ac.uk/pdbsum/5cf2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cf2 ProSAT]</span></td></tr> | ||
| Line 10: | Line 11: | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/LIMA_RHOER LIMA_RHOER]] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates. | [[http://www.uniprot.org/uniprot/LIMA_RHOER LIMA_RHOER]] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Epoxide hydrolase 3D structures|Epoxide hydrolase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Mycobacterium erythropolis gray and thornton 1928]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Limonene-1,2-epoxide hydrolase]] | [[Category: Limonene-1,2-epoxide hydrolase]] | ||
[[Category: Reetz, M T]] | [[Category: Reetz, M T]] | ||
Revision as of 11:36, 27 March 2020
Crystal Structure of the I80Y/L114V/I116V mutant of LEH
| |||||||||||
