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5cjp

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'''Unreleased structure'''
 
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The entry 5cjp is ON HOLD until Aug 31 2017
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==The Structural Basis for Cdc42-Induced Dimerization of IQGAPs==
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<StructureSection load='5cjp' size='340' side='right' caption='[[5cjp]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors: Worthylake, D.K., Boyapati, V.K., LeCour Jr, L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5cjp]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CJP FirstGlance]. <br>
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Description: The Structural Basis for Cdc42-Induced Dimerization of IQGAPs
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjp OCA], [http://pdbe.org/5cjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cjp RCSB], [http://www.ebi.ac.uk/pdbsum/5cjp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cjp ProSAT]</span></td></tr>
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[[Category: Boyapati, V.K]]
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</table>
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[[Category: Lecour Jr, L]]
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== Function ==
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[[Category: Worthylake, D.K]]
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[[http://www.uniprot.org/uniprot/IQGA2_HUMAN IQGA2_HUMAN]] Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.
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__TOC__
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</StructureSection>
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[[Category: Boyapati, V K]]
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[[Category: Jr, L LeCour]]
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[[Category: Worthylake, D K]]
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[[Category: Iqgap2 gap related domain x-ray gtpase interactions complex cdc42]]
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[[Category: Protein binding]]

Revision as of 16:19, 10 August 2016

The Structural Basis for Cdc42-Induced Dimerization of IQGAPs

5cjp, resolution 2.60Å

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