5kuk
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant== | |
| - | + | <StructureSection load='5kuk' size='340' side='right' caption='[[5kuk]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5kuk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KUK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMU:DECYL-BETA-D-MALTOPYRANOSIDE'>DMU</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kum|5kum]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kuk OCA], [http://pdbe.org/5kuk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kuk RCSB], [http://www.ebi.ac.uk/pdbsum/5kuk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kuk ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KCJ12_CHICK KCJ12_CHICK]] Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification is probably due to the blockage of outward current by cytoplasmic polyamines and/or magnesium ions.<ref>PMID:20019282</ref> <ref>PMID:21874019</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Heyman, S]] | ||
| + | [[Category: Lee, S J]] | ||
| + | [[Category: Nichols, C G]] | ||
| + | [[Category: Ren, F]] | ||
| + | [[Category: Yuan, P]] | ||
| + | [[Category: Metal transport]] | ||
| + | [[Category: Metal transport kir 2 2 k62w mutant structure]] | ||
Revision as of 16:29, 10 August 2016
Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant
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