5djt
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5djt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5djt OCA], [http://pdbe.org/5djt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5djt RCSB], [http://www.ebi.ac.uk/pdbsum/5djt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5djt ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5djt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5djt OCA], [http://pdbe.org/5djt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5djt RCSB], [http://www.ebi.ac.uk/pdbsum/5djt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5djt ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | <div style="background-color:#fffaf0;"> | ||
+ | == Publication Abstract from PubMed == | ||
+ | LOVTRAP is an optogenetic approach for reversible light-induced protein dissociation using protein A fragments that bind to the LOV domain only in the dark, with tunable kinetics and a >150-fold change in the dissociation constant (Kd). By reversibly sequestering proteins at mitochondria, we precisely modulated the proteins' access to the cell edge, demonstrating a naturally occurring 3-mHz cell-edge oscillation driven by interactions of Vav2, Rac1, and PI3K proteins. | ||
+ | |||
+ | LOVTRAP: an optogenetic system for photoinduced protein dissociation.,Wang H, Vilela M, Winkler A, Tarnawski M, Schlichting I, Yumerefendi H, Kuhlman B, Liu R, Danuser G, Hahn KM Nat Methods. 2016 Jul 18. doi: 10.1038/nmeth.3926. PMID:27427858<ref>PMID:27427858</ref> | ||
+ | |||
+ | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
+ | </div> | ||
+ | <div class="pdbe-citations 5djt" style="background-color:#fffaf0;"></div> | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> |
Revision as of 08:00, 27 July 2016
Crystal structure of LOV2 (C450A) domain in complex with Zdk2
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