This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5gns
From Proteopedia
(Difference between revisions)
m (Protected "5gns" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structures of human Mitofusin 1 provide insight into mitochondrial tethering== | |
| - | + | <StructureSection load='5gns' size='340' side='right' caption='[[5gns]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5gns]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GNS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GNS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gnt|5gnt]], [[5gnr|5gnr]], [[5gnu|5gnu]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gns OCA], [http://pdbe.org/5gns PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gns RCSB], [http://www.ebi.ac.uk/pdbsum/5gns PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gns ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MFN1_HUMAN MFN1_HUMAN]] Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.<ref>PMID:11181170</ref> <ref>PMID:12475957</ref> <ref>PMID:12759376</ref> <ref>PMID:23921378</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Guo, X]] | ||
| + | [[Category: Hu, J]] | ||
| + | [[Category: Hu, X]] | ||
| + | [[Category: Huang, X]] | ||
| + | [[Category: Lou, Z]] | ||
| + | [[Category: Qi, Y]] | ||
| + | [[Category: Rao, Z]] | ||
| + | [[Category: Yan, L]] | ||
[[Category: Yu, C]] | [[Category: Yu, C]] | ||
| - | [[Category: | + | [[Category: Zhou, X]] |
| + | [[Category: Bdlp-like folding]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Mitofusin 1]] | ||
Revision as of 02:12, 11 December 2016
Structures of human Mitofusin 1 provide insight into mitochondrial tethering
| |||||||||||
Categories: Guo, X | Hu, J | Hu, X | Huang, X | Lou, Z | Qi, Y | Rao, Z | Yan, L | Yu, C | Zhou, X | Bdlp-like folding | Hydrolase | Mitofusin 1
