5l0o
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions== | |
| - | + | <StructureSection load='5l0o' size='340' side='right' caption='[[5l0o]], [[Resolution|resolution]] 2.36Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5l0o]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L0O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i6x|3i6x]]</td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l0o OCA], [http://pdbe.org/5l0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l0o RCSB], [http://www.ebi.ac.uk/pdbsum/5l0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l0o ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IQGA1_HUMAN IQGA1_HUMAN]] Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.<ref>PMID:15695813</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Liu, J]] | [[Category: Liu, J]] | ||
[[Category: Worthylake, D]] | [[Category: Worthylake, D]] | ||
| + | [[Category: Calponin homology]] | ||
| + | [[Category: Disulfide-bonded dimer]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 17:11, 3 October 2016
IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions
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