3u06
From Proteopedia
(Difference between revisions)
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==Crystal structure of the kinesin-14 NcdG347D== | ==Crystal structure of the kinesin-14 NcdG347D== | ||
| - | <StructureSection load='3u06' size='340' side='right' caption='[[3u06]], [[Resolution|resolution]] 2.35Å' scene=''> | + | <StructureSection load='3u06' size='340' side='right'caption='[[3u06]], [[Resolution|resolution]] 2.35Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3u06]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3u06]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U06 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CA(ND), CG7831, ncd, non-claret disjunctional ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CA(ND), CG7831, ncd, non-claret disjunctional ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u06 OCA], [https://pdbe.org/3u06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u06 RCSB], [https://www.ebi.ac.uk/pdbsum/3u06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u06 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/NCD_DROME NCD_DROME]] NCD is required for normal chromosomal segregation in meiosis, in females, and in early mitotic divisions of the embryo. The NCD motor activity is directed toward the microtubule's minus end.<ref>PMID:2146510</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drome]] | [[Category: Drome]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Endow, S A]] | [[Category: Endow, S A]] | ||
[[Category: IV, C W.Pemble]] | [[Category: IV, C W.Pemble]] | ||
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[[Category: Cell division]] | [[Category: Cell division]] | ||
[[Category: Kinesin-14]] | [[Category: Kinesin-14]] | ||
| - | [[Category: Microtubule binding]] | ||
[[Category: Microtubule]] | [[Category: Microtubule]] | ||
| + | [[Category: Microtubule binding]] | ||
[[Category: Molecular motor]] | [[Category: Molecular motor]] | ||
[[Category: Motor domain]] | [[Category: Motor domain]] | ||
Revision as of 05:52, 13 July 2022
Crystal structure of the kinesin-14 NcdG347D
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