This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3rks
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) K176P mutant== | ==Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) K176P mutant== | ||
| - | <StructureSection load='3rks' size='340' side='right' caption='[[3rks]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='3rks' size='340' side='right'caption='[[3rks]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3rks]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3rks]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Cassava Cassava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RKS FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rkt|3rkt]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3rkt|3rkt]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3983 Cassava])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lyase Lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.46 and 4.1.2.47 4.1.2.46 and 4.1.2.47] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rks OCA], [https://pdbe.org/3rks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rks RCSB], [https://www.ebi.ac.uk/pdbsum/3rks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rks ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/HNL_MANES HNL_MANES]] Involved in cyanogenesis, the release of HCN from injured tissues. Decomposes a varieties of (R) or (S) cyanohydrins into HCN and the corresponding aldehydes and ketones. The natural substrate of this enzyme is (S)-acetone cyanohydrin. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cassava]] | [[Category: Cassava]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Asano, Y]] | [[Category: Asano, Y]] | ||
Revision as of 10:14, 22 June 2022
Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) K176P mutant
| |||||||||||
