4eza

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==Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2==
==Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2==
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<StructureSection load='4eza' size='340' side='right' caption='[[4eza]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='4eza' size='340' side='right'caption='[[4eza]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4eza]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EZA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4eza]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EZA FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IQGAP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eza OCA], [https://pdbe.org/4eza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eza RCSB], [https://www.ebi.ac.uk/pdbsum/4eza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eza ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eza OCA], [http://pdbe.org/4eza PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4eza RCSB], [http://www.ebi.ac.uk/pdbsum/4eza PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4eza ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IQGA2_HUMAN IQGA2_HUMAN]] Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.
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[https://www.uniprot.org/uniprot/IQGA2_HUMAN IQGA2_HUMAN] Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Aalten, D M.F Van]]
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[[Category: Large Structures]]
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[[Category: Agacan, M]]
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[[Category: Agacan M]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Batty, I H]]
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[[Category: Batty IH]]
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[[Category: Bochkarev, A]]
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[[Category: Bochkarev A]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Crombet, L]]
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[[Category: Crombet L]]
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[[Category: Dixon, M J]]
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[[Category: Dixon MJ]]
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[[Category: Downes, C P]]
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[[Category: Downes CP]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Gray, A]]
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[[Category: Gray A]]
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[[Category: Leslie, N R]]
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[[Category: Leslie NR]]
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[[Category: Nedyalkova, L]]
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[[Category: Nedyalkova L]]
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[[Category: Park, H]]
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[[Category: Park H]]
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[[Category: Structural genomic]]
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[[Category: Schenning M]]
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[[Category: Schenning, M]]
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[[Category: Tempel W]]
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[[Category: Tempel, W]]
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[[Category: Tong Y]]
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[[Category: Tong, Y]]
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[[Category: Van Aalten DMF]]
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[[Category: Weigelt, J]]
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[[Category: Weigelt J]]
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[[Category: Zhong, N]]
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[[Category: Zhong N]]
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[[Category: Gap]]
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[[Category: Sgc]]
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[[Category: Signaling protein]]
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Revision as of 04:24, 7 October 2022

Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2

PDB ID 4eza

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