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3o2d
From Proteopedia
(Difference between revisions)
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==Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody== | ==Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody== | ||
| - | <StructureSection load='3o2d' size='340' side='right' caption='[[3o2d]], [[Resolution|resolution]] 2.19Å' scene=''> | + | <StructureSection load='3o2d' size='340' side='right'caption='[[3o2d]], [[Resolution|resolution]] 2.19Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3o2d]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3o2d]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O2D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O2D FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD4 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o2d OCA], [https://pdbe.org/3o2d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o2d RCSB], [https://www.ebi.ac.uk/pdbsum/3o2d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o2d ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[CD4|CD4]] | + | *[[CD4 3D structures|CD4 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Chen, B]] | [[Category: Chen, B]] | ||
Revision as of 07:14, 12 May 2022
Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody
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