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4g41
From Proteopedia
(Difference between revisions)
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==Crystal structure of s-adenosylhomocysteine nucleosidase from streptococcus pyogenes in complex with 5-methylthiotubericidin== | ==Crystal structure of s-adenosylhomocysteine nucleosidase from streptococcus pyogenes in complex with 5-methylthiotubericidin== | ||
| - | <StructureSection load='4g41' size='340' side='right' caption='[[4g41]], [[Resolution|resolution]] 1.45Å' scene=''> | + | <StructureSection load='4g41' size='340' side='right'caption='[[4g41]], [[Resolution|resolution]] 1.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4g41]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4g41]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_ATCC_10782 Streptococcus pyogenes ATCC 10782]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G41 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G41 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g41 OCA], [https://pdbe.org/4g41 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g41 RCSB], [https://www.ebi.ac.uk/pdbsum/4g41 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g41 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| - | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/E0PXI9_STRPY E0PXI9_STRPY]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).[SAAS:SAAS010049_004_034880] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Streptococcus pyogenes | + | [[Category: Large Structures]] |
| - | [[Category: Anderson | + | [[Category: Streptococcus pyogenes ATCC 10782]] |
| - | [[Category: Brown | + | [[Category: Anderson BF]] |
| - | [[Category: Evans | + | [[Category: Brown RL]] |
| - | [[Category: Frohlich | + | [[Category: Evans GB]] |
| - | [[Category: Norris | + | [[Category: Frohlich R]] |
| - | [[Category: Ponniah | + | [[Category: Norris GE]] |
| - | [[Category: Tyler | + | [[Category: Ponniah K]] |
| - | + | [[Category: Tyler PC]] | |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 20:23, 19 October 2022
Crystal structure of s-adenosylhomocysteine nucleosidase from streptococcus pyogenes in complex with 5-methylthiotubericidin
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