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4l5f
From Proteopedia
(Difference between revisions)
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==Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII== | ==Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII== | ||
| - | <StructureSection load='4l5f' size='340' side='right' caption='[[4l5f]], [[Resolution|resolution]] 2.45Å' scene=''> | + | <StructureSection load='4l5f' size='340' side='right'caption='[[4l5f]], [[Resolution|resolution]] 2.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4l5f]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4l5f]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L5F FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [https://pdbe.org/4l5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [https://www.ebi.ac.uk/pdbsum/4l5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l5f ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/Q8BE40_9FLAV Q8BE40_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774] |
==See Also== | ==See Also== | ||
| - | *[[3D structures of | + | *[[Antibody 3D structures|Antibody 3D structures]] |
| + | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | ||
| + | *[[3D structures of non-human antibody|3D structures of non-human antibody]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Dengue virus 1]] | [[Category: Dengue virus 1]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | + | [[Category: Edeling MA]] | |
| - | [[Category: Edeling | + | [[Category: Fremont DH]] |
| - | [[Category: Fremont | + | [[Category: Nelson CA]] |
| - | [[Category: Nelson | + | |
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Current revision
Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
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