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4ux6
From Proteopedia
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<StructureSection load='4ux6' size='340' side='right' caption='[[4ux6]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='4ux6' size='340' side='right' caption='[[4ux6]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ux6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UX6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UX6 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4ux6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UX6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UX6 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=YWO:O-(5-METHYL-2-NITROPHENYL)-D-TYROSINAMIDE'>YWO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=YWO:O-(5-METHYL-2-NITROPHENYL)-D-TYROSINAMIDE'>YWO</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_synthase_(NADPH_dependent) Nitric-oxide synthase (NADPH dependent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_synthase_(NADPH_dependent) Nitric-oxide synthase (NADPH dependent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] </span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Lk3 transgenic mice]] | ||
[[Category: Andrews, G]] | [[Category: Andrews, G]] | ||
[[Category: Beaton, H G]] | [[Category: Beaton, H G]] | ||
Revision as of 07:55, 17 January 2018
The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)
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Categories: Lk3 transgenic mice | Andrews, G | Beaton, H G | Birkinshaw, T | Boughton-Smith, N | Cheshire, D R | Connolly, S | Cook, T R | Cooper, A | Cooper, S L | Cox, D | Dixon, J | Gensmantel, N | Hamley, P J | Harrison, R | Hartopp, P | Kack, H | Luker, T | Mete, A | Millichip, I | Nicholls, D J | Pimm, A D | St-Gallay, S A | Wallace, A V | Drug design | Oxidoreductase
