4k8g

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==Crystal structure of D-Mannonate dehydratase from Novosphingobium aromaticivorans mutant (V161A, R163A, K165G, L166A, Y167G, Y168A, E169G)==
==Crystal structure of D-Mannonate dehydratase from Novosphingobium aromaticivorans mutant (V161A, R163A, K165G, L166A, Y167G, Y168A, E169G)==
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<StructureSection load='4k8g' size='340' side='right' caption='[[4k8g]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
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<StructureSection load='4k8g' size='340' side='right'caption='[[4k8g]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4k8g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Novad Novad]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K8G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K8G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4k8g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Novosphingobium_aromaticivorans_DSM_12444 Novosphingobium aromaticivorans DSM 12444]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K8G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K8G FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qjj|2qjj]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k8g OCA], [https://pdbe.org/4k8g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k8g RCSB], [https://www.ebi.ac.uk/pdbsum/4k8g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k8g ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Saro_3675 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=279238 NOVAD])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k8g OCA], [http://pdbe.org/4k8g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k8g RCSB], [http://www.ebi.ac.uk/pdbsum/4k8g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k8g ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MAND_NOVAD MAND_NOVAD] Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:17944491</ref> <ref>PMID:24697546</ref>
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==See Also==
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*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Novad]]
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[[Category: Large Structures]]
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[[Category: Gerlt, J A]]
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[[Category: Novosphingobium aromaticivorans DSM 12444]]
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[[Category: Lukk, T]]
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[[Category: Gerlt JA]]
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[[Category: Nair, S K]]
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[[Category: Lukk T]]
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[[Category: Wichelecki, D]]
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[[Category: Nair SK]]
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[[Category: Metal binding protein]]
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[[Category: Wichelecki D]]
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[[Category: Tim barrel]]
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Revision as of 11:45, 30 November 2022

Crystal structure of D-Mannonate dehydratase from Novosphingobium aromaticivorans mutant (V161A, R163A, K165G, L166A, Y167G, Y168A, E169G)

PDB ID 4k8g

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