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4eq5

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==DNA ligase from the archaeon Thermococcus sibiricus==
==DNA ligase from the archaeon Thermococcus sibiricus==
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<StructureSection load='4eq5' size='340' side='right' caption='[[4eq5]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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<StructureSection load='4eq5' size='340' side='right'caption='[[4eq5]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4eq5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thesm Thesm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EQ5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4eq5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_sibiricus_MM_739 Thermococcus sibiricus MM 739]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EQ5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cfm|2cfm]], [[3gde|3gde]], [[2hiv|2hiv]], [[3rr5|3rr5]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eq5 OCA], [https://pdbe.org/4eq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eq5 RCSB], [https://www.ebi.ac.uk/pdbsum/4eq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eq5 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lig, Thermostable ATP-dependent DNA ligase gene Tsib_0885, TSIB_0885 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=604354 THESM])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(ATP) DNA ligase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.1 6.5.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eq5 OCA], [http://pdbe.org/4eq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4eq5 RCSB], [http://www.ebi.ac.uk/pdbsum/4eq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4eq5 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/C6A2U9_THESM C6A2U9_THESM]] DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.[HAMAP-Rule:MF_00407]
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[[https://www.uniprot.org/uniprot/C6A2U9_THESM C6A2U9_THESM]] DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.[HAMAP-Rule:MF_00407]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[DNA ligase|DNA ligase]]
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*[[DNA ligase 3D structures|DNA ligase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thesm]]
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[[Category: Large Structures]]
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[[Category: Bezsudnova, E Y]]
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[[Category: Thermococcus sibiricus MM 739]]
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[[Category: Dorokhov, B D]]
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[[Category: Bezsudnova EY]]
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[[Category: Dorovatovskiy, P V]]
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[[Category: Dorokhov BD]]
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[[Category: Kovalchuk, M V]]
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[[Category: Dorovatovskiy PV]]
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[[Category: Petrova, T]]
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[[Category: Kovalchuk MV]]
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[[Category: Polyakov, K M]]
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[[Category: Petrova T]]
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[[Category: Popov, V O]]
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[[Category: Polyakov KM]]
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[[Category: Ravin, N V]]
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[[Category: Popov VO]]
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[[Category: Skryabin, K G]]
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[[Category: Ravin NV]]
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[[Category: Slutskaya, E S]]
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[[Category: Skryabin KG]]
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[[Category: Adenylation domain]]
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[[Category: Slutskaya ES]]
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[[Category: Archaeon thermococcus sibiricus]]
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[[Category: Atp-dependent thermostable dna ligase]]
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[[Category: Dna-binding domain]]
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[[Category: Ligase]]
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Revision as of 07:23, 28 September 2022

DNA ligase from the archaeon Thermococcus sibiricus

PDB ID 4eq5

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